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For instance, LUXendins (such as LUXendin551, LUXendin645, or LUXendin762) are antagonistic red and far-red fluorescent probes that reveal GLP-1 receptor organization into membrane nanodomains and distinct cell subpopulations in pancreatic islets and brain
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Several large-scale trials, including the LEADER and SUSTAIN-6 studies, demonstrated reduced cardiovascular risk in patients at high baseline risk